Research Fellow (CSCB/OST), Singapore

Job Title: Research Fellow (CSCB/OST)
University-Level Unit: Duke-NUS Medical School
Faculty/Department-Level Unit: Office of Research
Employee Category: Research Staff
Location_ONB: Outram Campus
Posting Start Date: 29/04/2026
Job Description
We are a fast-moving translational research lab driven by the need to develop curative therapies for chronic myeloid leukaemia (CML) and Asian-specific solid tumours including nasopharyngeal cancer. Our team combines leading-edge multi-omics single-cell profiling with AI/ML-guided discovery to uncover new mechanisms of targeted drug resistance, then rigorously validates these findings using state-of-the-art platforms including iPSC-based technologies, advanced in vitro systems, and in vivo models. Our current work spans global clinical biomarker studies to predict drug resistance at diagnosis, and next-generation therapeutic strategies to eliminate persistent leukaemia stem cells (LSCs) in minimal residual disease and prevent disease transformation- ranging from NK cell-based approaches to small molecule-targeting of high-risk epigenetic cell states we have identified.
Key Responsibilities
Independently carry out the design and execution of experimental research required by the research component of the project. Design and execute experiments, ensuring high-quality and reproducible outcomes. Translate research findings into publications, presentations, and new research directions. Develop plans for independent research which could have a considerable influence and impact on the relevant field attracting research funding. Provide support for external grant/protocol development, study design and management of research activities. Provide guidance and mentorship to undergraduate students / research assistants, contributing to team development and scientific direction. Perform other related duties incidental to the work described therein.
Job Requirements
PhD in a relevant scientific discipline (or equivalent postgraduate degree with strong research track record). Strong laboratory experimental experience; ability to work independently and rigorously. Experience with iPSC-based platforms, multi-colour flow cytometry, and mouse models. Solid grounding in the scientific context of the research area and confidence supporting diverse research activities. Proven publication track record (including high-impact outputs). Demonstrated and growing research independence, with initiative and ambition to build new directions. Excellent scientific writing, critical thinking, communication, and presentation skills.
We regret that only shortlisted candidates will be notified.
More Information
Location: Outram Campus
Organization: Duke-NUS Medical School
Department : Office of Research
Employee Referral Eligible: No
Job requisition ID : 32661